21 CFR Osmometers

MEASURING PRINCIPLE

Osmometers are instruments for determination of osmotic concentration of aqueous solutions. A small amount of aqueous solution (30µl~50µl) is used to measure the freezing point. Based on this value the instrument calculates the osmotic concentration (=osmotic pressure) and displays it. The freezing point of aqueous solutions is measured. The depression of freezing point compared to pure water is direct related to the osmotic concentration. Pure water freezes at 0°C, an aqueous solution with an osmolality of 1 osmol/kg water at –1.858°C. 1 Mol of a substance dissolved in 1 kg of water gives a solution with an osmotic concentration of 1 osmol/kg water only if it is an ideal solution and if the substance does not dissociate.

Micro-Volume Freezing Point Osmometer
Model: Osmo210(For Pharmaceutical customers)


DESCRIPTION

It is an automatic freezing point osmometer with sample volume of 30~50ul and specially designed for biotech industry with very powerful 21 CFR Part 11 related features incl. multi-level pass word protected user accounts, time stamped audit trail with ability of linking sample ID and user ID to test results for improved traceability. Other useful features include touch screen user interface, automatic measuring head operation, 32G mass memory for long term data storage and user defined calibration points. All above useful features make Osmo210 an ideal osmometer for biotech industry.

FEATURES & FUNCTIONS 

  • FREEZING POINT DEPRESSION TECHNOLOGY
    Osmo210 determines the osmolality of solutions using freezing point depression technology, which is the industry preferred method for determining sample concentration because it accounts for all solutes in solution.
  • SOLID STATE COOLING TECHNOLOGY
    Osmo210 cools samples by Peltier elements. No cooling liquid, no maintenance.
  • 21 CFR PART 11 RELATED FEATURES
    Multi-level user accounts could be created without an external PC. The number of accounts is unlimited. All user
    accounts are password protected with the ability to link sample ID and user ID to test results for improved traceability.
  • TOUCH SCREEN USER INTERFACE
    Osmo210 is easy-to-use with an intuitive, color-coded menu-driven operating system.
  • STURDY AND DURABLE STAINLESS STEEL THERMISTOR
    It ensures high measurement precision, and is more durable than glass thermistors. The stainless steel thermistor is easy to be cleaned by any non-woven tissue to eliminate sample carryover.
  • IR SENSOR AT SAMPLE POSITION
    IR sensor could protect the thermistor from going down in case of missing sample tube. This function could avoid the damage of expensive thermistor.
  • USER-DEFINED CALIBRATION POINTS
    Variable calibration point fully meets the requirements of  Pharmacopoeia. Default calibration point of 50 and 850 mOsm are also available at user’s option.
  • USER-DEFINED SUPERCOOL POINT
    User can adjust supercool point to measure samples with lower freezing point.
  • STABLE CALIBRATIONS
    The unit has been calibrated in factory and ready to use. The calibration is very stable.
  • COOLING ADAPTATION
    Osmo 210 is equipped with a variable speed fan to remove heat when the osmometer is working in higher ambient temperature.
  • READY TO CONNECT WITH PC, BARCODE READER AND EXTERNAL PRINTER
    Osmo210 is equipped Mini USB, RS 232 port, which can easily output, download and view log of all users including the calibration data, test results, working status, error message and events.
  • ON-BOARD STATISTICAL ANALYSIS
    Osmo210 calculates the repeatability, standard deviation and mean value instantly. The date, time and language are adjustable through built-in menu.
  • 32G MASS MEMORY
    For long term data storage purpose.

 

Micro-Volu me Freezing Point Osmometer
Model: Osmo 310(For Scientific Research customers)

 

DESCRIPTION

Osmo 310 is an automatic freezing point osmometer with sample volume of 30~50ul and specially designed for scientific research customers. Useful features include touch screen user interface, automatic measuring head operation, 32G mass memory make Osmo310 well accepted by customers of universities and scientific research institutes.

FEATURES & FUNCTIONS

  • FREEZING POINT DEPRESSION TECHNOLOGY
    Osmo310 determines the osmolality of solutions using freezing point depression technology, which is the industry preferred method for determining sample concentration because it accounts for all solutes in solution.
  • SOLID STATE COOLING TECHNOLOGY
    Osmo310 cools samples by Peltier elements. No cooling liquid, no maintenance.

  • TOUCH SCREEN USER INTERFACE
    Osmo310 is easy-to-use with an intuitive, color-coded menu-driven operating system.
  • STURDY AND DURABLE STAINLESS STEEL THERMISTOR
    It ensures high measurement precision, and is more durable than glass thermistors. The stainless steel thermistor is easy to be cleaned by any non-woven tissue to eliminate sample carryover.
  • IR SENSOR AT SAMPLE POSITION
    IR sensor could protect the thermistor from going down in case of missing sample tube. This function could avoid the damage of expensive thermistor.
  • USER-DEFINED CALIBRATION POINTS
    Variable calibration point fully meets the requirements of Pharmacopoeia. Default calibration point of 50 and 850 mOsm are also available at user’s option.
  • USER-DEFINED SUPERCOOL POINT
    User can adjust supercool point to measure samples with lower freezing point.
  • STABLE CALIBRATIONS
    The unit has been calibrated in factory and ready to use. Occasional checks show that the calibration is very stable.
  • COOLING ADAPTATION
    Osmo310 is equipped with a variable speed fan to remove heat when the osmometer is working in higher ambient temperature.
  • READY TO CONNECT WITH PC, BARCODE READER AND EXTERNAL PRINTER
    Osmo310 is equipped Mini USB, RS 232 port, which can easily output, download and view log of all users including the calibration data, test results, working status, error message and events.
  • 32G MASS MEMORY
    For long term data storage purpose.

 

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